There had been speculation that the 26-year-old actress would make a guest appearance in the fifth instalment of the spoof comedy series, following cameos by Carmen Electra, Charlie Sheen and Pamela Anderson in previous films.
Sources had told the New York Post that Lindsay met with film boss Bob Weinstein about possibly joining the cast opposite High School Musical star Ashley Tisdale, but a spokesperson for Dimension Films said the actress is "not confirmed" to be in the film.
Malcolm D Lee is set to direct the latest film, which is co-written by David Zucker and Pat Proft, and is scheduled for release in spring 2013.
Anna Faris starred in the first four Scary films.
Lindsay has been making a career comeback after being let off formal probation in March, having completed filming Lifetime TV drama Liz And Dick, in which she plays Elizabeth Taylor.
"That's a wrap on Liz And Dick - thank you to all my fans, crew members, friends and Lifetime!" she tweeted after the shoot on July 2.
After being treated by paramedics for exhaustion during the Liz And Dick shoot, she is set to start filming Paul Shrader's big-screen adaptation of Bret Easton Ellis' thriller The Canyons alongside Canadian actor Nolan Gerard Funk.
